Modafinil in elderly patients
Modafinil In Elderly Patients
To the best of our knowledge, as of January 22, 2007, this is the first report of modafinil treatment of apathy syndrome effects, close monitoring for adverse ef fects is necessary in.There is evidence that D 1 and D 2 receptors are targeted by modafinil.Sir, Treatment of bipolar depression in the elderly is challenging due to the presence of medical comorbidities and it is often modafinil in elderly patients resistant to treatment.Therefore, consideration should be given to the use of lower doses and close monitoring in this population [see Dosage and Administration ( 2.Apathy improved significantly after treatment with modafinil in this patient.[] Modafinil with its novel mechanism of action, utilizing multiple neurotransmitter systems such as dopamine, hypocretin, histamine, epinephrine, gamma-aminobutyric acid, and glutamate, is a well-tolerated medication with minimum drug.The safety and tolerability of modafinil was evaluated in six randomized, double-blind, placebo-controlled studies in patients with hypersomnolence and showed infrequent (.4 ) and Clinical Pharmacology ( 12.Due to its relative lack of drug interactions, modafinil is a good alternative for elderly patients, who often receive multiple medications.5 Patients with impaired elimination of modafinil may be susceptible to developing dyskinesias In elderly patients, elimination of Modafinil and its metabolites may be reduced as a consequence of aging.Breastfeeding There are no adequate studies in women for determining infant risk when using this medication during breastfeeding However, elderly patients may have a slower removal of modafinil from the body, which may require an adjustment in the dose for patients receiving modafinil.3 This presentation is remarkably similar to previous cases of orofacial dyskinesia reported in patients receiving modafinil 1, 4 and adrafinil.44–49 Modafinil is a useful adjunct for partial responders to SRIs, resulting in rapid mood improvement and decreased fatigue.Elderly patients with dementia.
Modafinil ou ritalina, modafinil in patients elderly
modafinil in elderly patients modafinil in elderly patients